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There is not such thing as a normal genome
Genome sequencing studies indicate that all humans carry many genetic variants predicted to cause loss of function (LoF) of protein-coding genes, suggesting unexpected redundancy in the human genome....
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Genomes in the Cloud
The Amazon Web Services (AWS – Biology section) just added the 2 TB of the 1,000 genome project. Far from being this a fad, the storage and analysis in the cloud seems to be a common practice for the...
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The New Biology
http://www.youtube.com/watch?v=sjTQD6E3lH4&w=400&h=233 Do you like the New Biology video? ... then surely you are interested in our work
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Nature journal highlighted our research
Our recent publication about the discovery of a new Ebola-like virus in Europe was highlighted in Nature
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Developing an European-American NGS Network Project
On November 14th 2013 the Kick-off event took place, announcing the beginning of the project Marie Curie-IRSES named “DEANN”. The DEANN project aims to strengthen collaborations between researchers in...
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Evolution- What Darwin Did Not Know – BBC Documentary
The Theory of Evolution by Natural Selection is one of the most successful achievements of science of all time
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De novo assembly of the Aedes aegypti genome using Hi-C yields chromosome...
The Zika outbreak, spread by the Aedes aegypti mosquito, highlights the need to create high-quality assemblies of large genomes in a rapid and cost-effective fashion. Here, we combine Hi-C data with...
View ArticleEdición génica y embriones humanos
Crear niños genéticamente modificados ya no es una fantasía de ciencia ficción; es un escenario futuro probable. El biólogo Paul Knoepfler estima que dentro de quince años, los científicos podrían usar...
View ArticleEpigenética y Comportamiento
Moshe Szyf es un pionero en el campo de la epigenética, su estudio se centra en cómo los seres vivos reprograman su genoma en respuesta a factores sociales como el estrés y la falta de alimentos. Su...
View ArticleGenoma Humano y Medicina Personalizada
Instintos, temores, y enfermedades están escritos en el genoma humano, el conjunto completo de instrucciones genéticas necesarias para construir un ser humano. Riccardo Sabatini, nos muestra como leer...
View ArticleSecuencias Aleatorias y Funcionales
Una fracción inesperadamente elevada de secuencias de nucleótidos y aminoácidos combinados aleatoriamente resultan biológicamente activos y puede influir en la aptitud de E.coli. Esto da credibilidad a...
View ArticleGenome-based diets maximise growth, fecundity, and lifespan
A moderate reduction in food intake, known as dietary restriction, protects against multiple ageing-related diseases and extends life span, but can also suppress growth and fertility. A research group...
View ArticleUsing CRISPR against cancer shows success in mice
Specifically targeting genomic rearrangements and mutations in tumor cells remains an elusive goal in cancer therapy. Here, we used Cas9-based genome editing to introduce the gene encoding the...
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